Since returning to television as an Emmy-nominated series regular with “The West Wing” in 1999, Rob Lowe has acted in and produced a dizzying number of television programs; as of this writing, he currently stars in two series, the Fox drama, “9-1-1 Lone Star,” and the Netflix comedy, “Unstable,” and he also hosted the now-canceled game show, “Mental Samurai.” Many of Lowe’s TV efforts have been hits, and though others haven’t fared as well, that doesn’t seem to have fazed Lowe in the least.

Among his misses that followed major hits was 2003’s “The Lyon’s Den” and 2004’s “Dr. Vegas,” which came and went following his departure from “The West Wing” in 2003. Lowe rebounded with “Brothers & Sisters” and “Parks and Recreation,” which preceded a veritable blitz of TV projects. Many of them drew excellent reviews, including the animated series, “Moonbeam City,” and “The Grinder,” though both were axed after just a single season. He joined the cast of the struggling medical drama, “Code Black,” in its second season but was unable to staunch the bleeding that led to its demise in Season 3.

Undaunted, Lowe launched “The Lowe Files,” an A&E series that sent him with sons John Owen and Edward in search of answers to unexplained mysteries. It vanished after nine episodes, but again, he rebounded with “Mental Samurai” and “9-1-1 Lone Star.” The latter series was renewed for a fourth season in 2023, the same year that Lowe and John Owen created “Unstable.”